AZD3759 hydrochloride

CAS No. 1626387-81-2

AZD3759 hydrochloride ( —— )

Catalog No. M18097 CAS No. 1626387-81-2

AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrantEGFRinhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 Get Quote
5MG 61 Get Quote
10MG 88 Get Quote
25MG 152 Get Quote
50MG 268 Get Quote
100MG 442 Get Quote
500MG 1008 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AZD3759 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrantEGFRinhibitor.
  • Description
    AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrantEGFRinhibitor. At KmATP concentrations, theIC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR (exon 19De); EGFR (L858R); EGFR (wt)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1626387-81-2
  • Formula Weight
    496.36
  • Molecular Formula
    C22H24Cl2FN5O3
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zeng Q, et al. J Med Chem. 2015 Oct 22;58(20):8200-15.
molnova catalog
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